IBD Research

 
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A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults With Crohn’s Disease - DINE-CD Study

JD Lewis, RS Sandler, C Brotherton, et al. Gastroenterology, 2021

This parallel group, randomized trial compared the effectiveness of the MD and SCD in resolving symptoms and inflammation among Crohn’s patients and found symptomatic remission was common with both diets. Read more here.

 
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Association of ultra-processed food intake with risk of inflammatory bowel disease: prospective cohort study

N Narula, E Wong, M Dehghan, et al. BMJ, 2021

This multinational prospective cohort study found that a higher intake of ultra-processed food was positively associated with risk of IBD. Read more here.

 
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The role of diet in the prevention and treatment of Inflammatory Bowel Disease

R Reddavide , O Rotolo, MG Caruso, et al. Acta Biomedica, 2018

This review summarizes the current knowledge of the interaction between diet, the microbiome and immune-modulation in IBD. The authors discuss the Mediterranean Diet as a tool for prevention and treatment of the disease and it’s symptoms. Read more here.

 
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Dietary Fructose Alters the Composition, Localization, and Metabolism of Gut Microbiota in Association With Worsening Colitis

DC Montrose, R. Nishiguchi, S Basu, et al. CMGH, 2020

This study concluded that excessive consumption of dietary fructose can induce colitis due to producing changes in the gut microbiome. Read more here.

 
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The Mycobiome: Role in health and disease, and as a potential probiotic target in gastrointestinal disease

CL Hager, MA Ghannoum. Digestive and Liver Disease, 2017.

This study found that Crohn’s disease patients tend to have higher levels of a fungus called Candida tropicalis as well as two bacteria, Escherichia coli and Serratia marcescens, compared to healthy subjects. Read more here.

 
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A Review of Dietary Therapy for IBD and a Vision for the Future

N Green, T Miller, D Suskind, D Lee. Nutrients, 2019.

This review discusses various dietary interventions, their ability to modulate the intestinal microbiome, and their efficacy in treating IBD. Read more here.

 
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Diet as a therapeutic option for adult inflammatory bowel disease

S Kakodkar, MDa, EA Mutlu, MD, MS, MBAb. Gastro Clin North Am., 2017.

This review looks at the literature on diet and IBD with focus on Enteral Nutrition, the SCD and low FODMAP diets. Read more here.

 
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Antibiotic use and the development of inflammatory bowel disease: a national case-control study in Sweden

L Nguyen, A Örtqvist,Y Cao, et al. Lancet Gastroenterol Hepatol, 2020.

This study looked at high cumulative exposure to systemic antibiotic therapy and it’s association with an increased risk of new-onset IBD and its subtypes. Read more here.

 
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Diet, Gut Microbiome and Epigenetics: Emerging Links with Inflammatory Bowel Diseases and Prospects for Management and Prevention

K Aleksandrova, B Romero-Mosquera, V Hernandez. Nutrients, 2017.

This review summarizes the current knowledge of the influence of diet on microbiome and epigenetics. The authors also discuss the possibility of increased gut inflammation resulting from an over abundance of calories and specific macronutrients as well as the importance of specific micronutrients in immune system modulation. Read more here.

 
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